SCHEMBL14280264

SCHEMBL14280264

CC(c1ccc(O)cc1)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(C)c1ccc(O)cc1)C3=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.55
APAF1 O14727 1/20 0.55
ESR1 P03372 5/20 0.42
ESR2 Q92731 5/20 0.42
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
DNMT3A Q9Y6K1 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.37
EP300 Q09472 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
KMT2A Q03164 1/20 0.36
ANPEP P15144 1/20 0.36
DPP4 P27487 1/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16321480 0.86 LMNA (0.51) POLBESR1ESR2PDCD1CD274
SCHEMBL6744615 0.86 LMNA (0.51) POLBESR1ESR2PDCD1CD274
SCHEMBL13878069 0.84 ALDH1A1 (0.41) POLBAPAF1NPC1RAB9ALMNA
SCHEMBL14280267 0.82 DNMT3A (0.42) POLBAPAF1NPC1RAB9ADNMT3A
SCHEMBL14280257 0.82 MET (0.40) POLBAPAF1LMNA
SCHEMBL14280266 0.82 PTGES (0.42) POLBAPAF1NPC1RAB9AKMT2A
SCHEMBL13878053 0.81 ALDH1A1 (0.46) POLBDNMT3AL3MBTL1LMNAKDM4E
SCHEMBL14280260 0.79 ALDH1A1 (0.45) POLBESR1L3MBTL1LMNAKDM4E
SCHEMBL23417382 0.79 MAPK1 (0.41) POLBAPAF1NPC1RAB9AL3MBTL1
SCHEMBL7647972 0.78 ALDH1A1 (0.45) ESR1ESR2PDCD1CD274L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080014520-A1 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
US-20080014520-A1 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
EP-1879076-A2 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor Samsung Electronics Co., Ltd. (KR) 2008-01-16 EP disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 US disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 US disclosed