Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RGS4 | P49798 | 4/20 | 0.41 |
| ▸ | RGS8 | P57771 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LGMN | Q99538 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280870 | 0.86 | RGS4 (0.43) | HPGDCYP3A4KMT2ARGS4RGS8 | |
| SCHEMBL4490611 | 0.73 | ROCK2 (0.53) | HPGDCYP3A4KMT2ARGS4RGS8 | |
| SCHEMBL13963463 | 0.70 | HPGD (0.43) | HPGDCYP3A4KMT2ALGMNGSK3A | |
| SCHEMBL30272686 | 0.68 | HPGD (0.50) | HPGDCYP3A4KMT2ARGS4RGS8 | |
| SCHEMBL5864333 | 0.68 | PTGS1 (0.49) | HPGDCYP3A4MAPK8MAPK9KDM4E | |
| SCHEMBL8985073 | 0.67 | GSK3B (0.67) | HPGDCYP3A4KMT2ARGS4RGS8 | |
| SCHEMBL14563447 | 0.67 | ALDH1A1 (0.47) | HPGDCYP3A4KMT2AALDH1A1GSK3A | |
| SCHEMBL3940708 | 0.66 | HPGD (0.64) | HPGDCYP3A4KMT2AALDH1A1LGMN | |
| SCHEMBL14408874 | 0.66 | KDM4E (0.47) | HPGDCYP3A4KMT2AALDH1A1GSK3A | |
| SCHEMBL3319539 | 0.65 | HDAC8 (0.44) | KMT2AALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | HPGD 921/4885CYP3A4 4656/4885KMT2A 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.