Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23281438 | 0.85 | GAA (0.60) | POLBMEN1KMT2AMAPK1GAA | |
| SCHEMBL29721853 | 0.82 | POLB (0.72) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL28734394 | 0.82 | POLB (0.72) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL12083396 | 0.81 | EP300 (0.57) | MEN1KMT2AALDH1A1EP300 | |
| SCHEMBL5144511 | 0.80 | POLB (0.86) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL31661769 | 0.79 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL7718043 | 0.79 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL3046406 | 0.79 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL7717051 | 0.79 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 | |
| SCHEMBL5656576 | 0.79 | POLB (0.69) | POLBMEN1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ECOLE NORMALE SUPERIEURE (FR) | 2022-12-29 | — | — | US | disclosed |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ECOLE NORMALE SUPERIEURE (FR) | 2022-12-29 | — | — | US | disclosed |
| CN-115209891-A | Analogs of N-acyl-homoserine lactones and pharmaceutical compositions containing the same | 索邦大学 | 2022-10-18 | — | — | CN | disclosed |
| EP-4048258-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SORBONNE UNIVERSITE (FR) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021078952-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SORBONNE UNIVERSITE (FR) | 2021-04-29 | — | — | WO | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | QRFPR, CASR, BLVRB | POLB 4596/4885MEN1 3649/4885KMT2A 3882/4885 |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AHCYL1, LTC4S, AHCY | POLB 4848/4885MEN1 1049/4885KMT2A 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.