Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | UBE2N | P61088 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139953 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27963355 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL13825654 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL7756046 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3344513 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL10605211 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL2385582 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL10607850 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL136612 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL10606337 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079802-A | Cationic lipids and compositions thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-20250352666-A1 | LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO (US) | 2025-11-20 | — | — | US | claimed |
| EP-4626409-A1 | SYNTHETIC SINGLE STRANDED NUCLEIC ACID COMPOSITIONS AND METHODS THEREOF | Generation Bio Co. (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250249123-A1 | LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. | 2025-08-07 | — | — | US | claimed |
| WO-2025127402-A1 | LIPID FOR ENHANCING IMMUNOGENICITY OF MRNA/LNP VACCINE | 한국생명공학연구원 | 2025-06-19 | — | — | WO | claimed |
| EP-4536197-A1 | LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | Generation Bio Co. (US) | 2025-04-16 | — | — | EP | claimed |
| US-12263228-B2 | Lipids and compositions thereof | GENERATION BIO CO. (US) | 2025-04-01 | — | — | US | claimed |
| WO-2024249298-A2 | MODIFIED CLOSED-ENDED DNA (CEDNA) VECTORS, COMPOSITIONS, AND USES THEREOF | GENERATION BIO CO. (US) | 2024-12-05 | — | — | WO | claimed |
| US-20240382432-A1 | SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO. | 2024-11-21 | — | — | US | claimed |
| US-20240299580-A1 | APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO. | 2024-09-12 | — | — | US | claimed |
| CN-117545469-A | Cationic lipids and compositions thereof | 世代生物公司 | 2024-02-09 | — | — | CN | claimed |
| WO-2023239756-A1 | LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO. (US) | 2023-12-14 | — | — | WO | claimed |
| CN-115745788-A | Ionizable lipid compound and preparation method and application thereof | 国家纳米科学中心 | 2023-03-07 | — | — | CN | claimed |
| WO-2023287861-A2 | SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO. (US) | 2023-01-19 | — | — | WO | claimed |
| CN-115504945-A | Ionizable heterocyclic lipid molecule and application thereof in preparation of lipid nanoparticles | 南京吉迈生物技术有限公司 | 2022-12-23 | — | — | CN | claimed |
| WO-2022266032-A1 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. (US) | 2022-12-22 | — | — | WO | claimed |
| WO-2022261101-A1 | APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | GENERATION BIO CO. (US) | 2022-12-15 | — | — | WO | claimed |
| WO-2022226008-A2 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. (US) | 2022-10-27 | — | — | WO | claimed |
| CN-114344278-A | Nucleic acid delivery vectors and uses thereof | 南京吉迈生物技术有限公司 | 2022-04-15 | — | — | CN | claimed |
| WO-2002087541-A1 | LIPID-BASED FORMULATIONS FOR GENE TRANSFER | PROTIVA BIOTHERAPEUTICS INC. (CA) | 2002-11-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299580-A1 | APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | LDLR, APOB, APOL1 | SPHK1 3627/4885CYP2D6 3964/4885LMNA 63/4885 |
| US-12263228-B2 | Lipids and compositions thereof | C1R, LIPG, LRBA | SPHK1 1286/4885CYP2D6 2994/4885LMNA 49/4885 |
| US-20250352666-A1 | LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | LIPA, EYA3, EYA2 | SPHK1 873/4885CYP2D6 4779/4885LMNA 305/4885 |
| US-20250249123-A1 | LIPIDS AND COMPOSITIONS THEREOF | C1R, LIPG, LRBA | SPHK1 1286/4885CYP2D6 2994/4885LMNA 49/4885 |
| US-20240382432-A1 | SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF | LNPEP, CD47, CD4 | SPHK1 2042/4885CYP2D6 4755/4885LMNA 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.