Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | BRAF | P15056 | 2/20 | 0.77 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.61 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133944 | 0.87 | BRAF (1.00) | ALDH1A1GAAHSD17B10BRAFPIK3CG | |
| SCHEMBL17522954 | 0.81 | BRAF (0.81) | ALDH1A1GAABRAFPIK3CGLMNA | |
| SCHEMBL25522708 | 0.80 | RXFP1 (0.74) | ALDH1A1GAAHSD17B10LMNAMAOA | |
| SCHEMBL16059176 | 0.80 | LMNA (0.62) | ALDH1A1GAABRAFPIK3CGLMNA | |
| SCHEMBL8291374 | 0.79 | PLD3 (0.81) | ALDH1A1GAAHSD17B10BRAFPIK3CG | |
| SCHEMBL16079515 | 0.78 | ALDH1A1 (0.69) | ALDH1A1GAAHSD17B10BRAFPIK3CG | |
| SCHEMBL29517871 | 0.78 | BRAF (0.76) | ALDH1A1HSD17B10BRAFPIK3CGLMNA | |
| SCHEMBL18834904 | 0.78 | TSHR (0.83) | ALDH1A1GAALMNANPSR1MAPT | |
| SCHEMBL18834862 | 0.78 | BRAF (0.63) | ALDH1A1GAAHSD17B10BRAFPIK3CG | |
| SCHEMBL19560418 | 0.77 | ALDH1A1 (0.71) | ALDH1A1GAAHSD17B10BRAFPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph (US) | 2008-01-17 | — | — | US | disclosed |
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph (US) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | CD74, HAVCR2, CD47 | ALDH1A1 3379/4885GAA 260/4885HSD17B10 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.