Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.76 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.76 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133944 | 0.86 | BRAF (1.00) | BRAFPIK3CGPLD3THRBALDH1A1 | |
| SCHEMBL17522954 | 0.85 | BRAF (0.81) | BRAFPIK3CGTHRBALDH1A1MAPT | |
| SCHEMBL25240049 | 0.80 | BRAF (0.66) | BRAFPIK3CGTHRBALDH1A1MAPT | |
| SCHEMBL14285657 | 0.78 | ALDH1A1 (0.78) | BRAFPIK3CGPLD3ALDH1A1MAPT | |
| SCHEMBL23493869 | 0.77 | PLD3 (0.58) | PLD3THRBALDH1A1MAPTHTT | |
| SCHEMBL17165784 | 0.75 | POLB (0.69) | BRAFPIK3CGTHRBALDH1A1MAPT | |
| SCHEMBL25210999 | 0.75 | ALDH1A1 (0.76) | BRAFPIK3CGTHRBALDH1A1MAPT | |
| SCHEMBL8291374 | 0.74 | PLD3 (0.81) | BRAFPIK3CGPLD3ALDH1A1MAPT | |
| SCHEMBL3372363 | 0.74 | ALDH1A1 (0.60) | BRAFPIK3CGPLD3THRBALDH1A1 | |
| SCHEMBL16029594 | 0.72 | MAOA (0.60) | BRAFPLD3THRBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071777-A1 | COMPOSITION AND METHOD FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE | 연세대학교 산학협력단 | 2022-04-07 | — | — | WO | claimed |
| WO-2022071777-A1 | COMPOSITION AND METHOD FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE | 연세대학교 산학협력단 | 2022-04-07 | — | — | WO | disclosed |