Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | TSHR | P16473 | 7/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290551 | 0.84 | TSHR (0.78) | ALDH1A1TSHRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL14285657 | 0.79 | ALDH1A1 (0.78) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL18834904 | 0.78 | TSHR (0.83) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16059176 | 0.78 | LMNA (0.62) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16029403 | 0.77 | ALDH1A1 (0.70) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16664758 | 0.77 | ALDH1A1 (0.67) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL23493915 | 0.74 | L3MBTL1 (0.56) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL23493987 | 0.74 | GAA (0.48) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL29517871 | 0.74 | BRAF (0.76) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16133944 | 0.74 | BRAF (1.00) | PLD3ALDH1A1TSHRSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | DNPEP, PREP, ANPEP | PLD3 1018/4885ALDH1A1 1025/4885TSHR 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.