Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447056 | 0.81 | FAAH (0.43) | CA2CA9TSHRFAAHCASP2 | |
| SCHEMBL20275340 | 0.81 | TSHR (0.44) | TSHR | |
| SCHEMBL14285708 | 0.80 | CA2 (0.36) | CA2CA9 | |
| SCHEMBL22508710 | 0.79 | EPHX2 (0.45) | TSHRFAAH | |
| SCHEMBL13655533 | 0.78 | FAAH (0.57) | FAAHCASP2DNM1 | |
| SCHEMBL13655575 | 0.78 | FAAH (0.57) | FAAHCASP2DNM1 | |
| SCHEMBL13655544 | 0.78 | FAAH (0.57) | FAAHCASP2DNM1 | |
| SCHEMBL13655546 | 0.78 | FAAH (0.57) | FAAHCASP2DNM1 | |
| SCHEMBL18845128 | 0.77 | HDAC3 (0.36) | CA2CA9CA1 | |
| SCHEMBL18845127 | 0.77 | CASP2 (0.50) | FAAHCASP2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242058-B2 | Reagents and methods for appending functional groups to proteins | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | PTMS, MTPN, FGB | CA2 3977/4885CA9 4576/4885TSHR 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.