Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132698 | 0.85 | HPGD (0.46) | MAPK1MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL19019884 | 0.79 | MAPT (0.43) | MAPK1MAPTGAACYP1A2CYP2D6 | |
| SCHEMBL20677872 | 0.78 | CYP2D6 (0.44) | MAPTCYP1A2CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL5730135 | 0.75 | CYP1A2 (0.70) | MAPK1MAPTCYP1A2CYP2D6HIF1A | |
| SCHEMBL14286351 | 0.75 | ALDH1A1 (0.48) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20685661 | 0.75 | KMT2A (0.47) | MAPTGAAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5127715 | 0.75 | ALDH1A1 (0.43) | MAPK1MAPTALDH1A1CYP1A2RAB9A | |
| SCHEMBL19019834 | 0.75 | PLA2G7 (0.47) | MAPK1MAPTALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29837525 | 0.74 | SMN1; SMN2 (0.49) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19019848 | 0.74 | SLC1A3 (0.42) | MAPK1MAPTALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | UNIV RUTGERS (US) | 2019-01-31 | — | — | US | disclosed |
| WO-2008025152-A1 | ANTIBACTERIAL AGENTS | MCMASTER UNIVERSITY (CA) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | ABCB11, SLC10A1, SLC47A1 | MAPK1 674/4885MAPT 4110/4885GAA 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.