Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286351 | 0.83 | ALDH1A1 (0.48) | KMT2AMAPTSMN1; SMN2GFERMCHR1 | |
| Hydrochloric Acid SCHEMBL29837525 | 0.82 | SMN1; SMN2 (0.49) | KMT2AMAPTSMN1; SMN2GFERTP53 | |
| SCHEMBL14286349 | 0.75 | MAPK1 (0.44) | KMT2AMAPTSMN1; SMN2GFERCYP1A2 | |
| SCHEMBL5132698 | 0.74 | HPGD (0.46) | KMT2AMAPTSMN1; SMN2GFERUSP2 | |
| SCHEMBL14286347 | 0.73 | GAA (0.47) | KMT2AMAPTSMN1; SMN2GFERMCHR1 | |
| SCHEMBL22263185 | 0.69 | RAB9A (0.41) | KMT2AMAPTSMN1; SMN2GFERUSP2 | |
| SCHEMBL19019884 | 0.69 | MAPT (0.43) | MAPTCYP1A2CYP2D6TP53GAA | |
| SCHEMBL5127715 | 0.68 | ALDH1A1 (0.43) | KMT2AMAPTSMN1; SMN2USP2CYP1A2 | |
| SCHEMBL943373 | 0.68 | MCHR1 (0.55) | KMT2AMAPTMCHR1CYP1A2CYP2D6 | |
| SCHEMBL19019834 | 0.66 | PLA2G7 (0.47) | KMT2AMAPTSMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | UNIV RUTGERS (US) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031624-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | ABCB11, SLC10A1, SLC47A1 | KMT2A 4605/4885MAPT 4110/4885SMN1; SMN2 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.