Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019834 | 0.76 | PLA2G7 (0.47) | PLA2G7MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL14286349 | 0.74 | MAPK1 (0.44) | MEN1MAPTKMT2ACYP1A2CYP2D6 | |
| SCHEMBL5132698 | 0.71 | HPGD (0.46) | MEN1MAPTKMT2ACYP1A2CYP2D6 | |
| SCHEMBL19061883 | 0.68 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2NPC1PKM | |
| SCHEMBL19019922 | 0.66 | MAPK1 (0.50) | PLA2G7MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL19019884 | 0.66 | MAPT (0.43) | MAPTCYP1A2CYP2D6TP53MAPK1 | |
| SCHEMBL19061887 | 0.66 | L3MBTL1 (0.51) | MEN1MAPTKMT2APKMRAB9A | |
| SCHEMBL19019870 | 0.65 | CHRNB2 (0.43) | MEN1KMT2ACYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL14286352 | 0.65 | OPRK1 (0.48) | MEN1MAPTKMT2ACYP3A4CYP1A2 | |
| SCHEMBL19061952 | 0.65 | CYP1A2 (0.51) | MEN1MAPTKMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |