Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061440 | 0.90 | MAPK1 (0.46) | MAPK1GAAOPRL1NPSR1TP53 | |
| SCHEMBL20918028 | 0.84 | CYP1A2 (0.44) | MAPK1CYP1A2CYP2D6HIF1AGAA | |
| SCHEMBL19019870 | 0.83 | CHRNB2 (0.43) | MAPK1TSHRNPSR1TP53 | |
| SCHEMBL19019834 | 0.83 | PLA2G7 (0.47) | MAPTMAPK1CYP1A2CYP2D6TP53 | |
| SCHEMBL19062009 | 0.83 | KDM4E (0.39) | MAPTMAPK1GAA | |
| SCHEMBL5132698 | 0.83 | HPGD (0.46) | MAPTDAOMAPK1CYP1A2CYP2D6 | |
| SCHEMBL20917965 | 0.82 | MAPK1 (0.41) | MAPTMAPK1CYP1A2CYP2D6HIF1A | |
| SCHEMBL19061872 | 0.80 | MAPK1 (0.41) | MAPTMAPK1CYP1A2CYP2D6GAA | |
| SCHEMBL22275605 | 0.79 | CYP1A2 (0.38) | MAPTDAOMAPK1CYP1A2CYP2D6 | |
| SCHEMBL19019905 | 0.79 | ALDH1A1 (0.40) | MAPTDAOCYP1A2CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3306354-B1 | ARTICLE COMPRISING A NANOLAMINATE COATING | CORP DE LECOLE POLYTECHNIQUE DE MONTREAL (CA) | 2021-12-22 | — | — | EP | disclosed |
| EP-3287818-B1 | OPHTHALMIC LENS HAVING INCREASED RESISTANCE TO HOT AND HUMID ENVIRONMENT | CORP DE LECOLE POLYTECHNIQUE DE MONTREAL (CA) | 2020-11-11 | — | — | EP | disclosed |
| EP-3306354-A1 | ARTICLE COMPRISING A NANOLAMINATE COATING | Corporation de L'Ecole Polytechnique de Montreal (CA) | 2018-04-11 | — | — | EP | disclosed |
| EP-3287818-A1 | OPHTHALMIC LENS HAVING INCREASED RESISTANCE TO HOT AND HUMID ENVIRONMENT | Corporation de L'Ecole Polytechnique de Montreal (CA) | 2018-02-28 | — | — | EP | disclosed |
| EP-3185050-A1 | OPTICAL ARTICLE COMPRISING A MULTILAYERED INTERFERENTIAL COATING OBTAINED FROM AN ORGANIC PRECURSOR OR A MIXTURE OF ORGANIC PRECURSORS | Essilor International (Compagnie Générale D'Optique) (FR) | 2017-06-28 | — | — | EP | disclosed |
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |