SCHEMBL14286751

SCHEMBL14286751

CC(=O)C1CSCC(=O)N1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.31
CAD P27708 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5683288 0.82 HTT (0.46) HTTKMT2ACAD
SCHEMBL8974020 0.82 HTT (0.46) HTTKMT2ACAD
SCHEMBL9201482 0.82 HTT (0.46) HTTKMT2ACAD
SCHEMBL10101200 0.79 KMT2A (0.53) KMT2A
SCHEMBL12359033 0.71
SCHEMBL12956482 0.71
SCHEMBL23370679 0.71 ITGB3 (0.33) KMT2A
SCHEMBL22749689 0.70
SCHEMBL22749694 0.70
SCHEMBL5324369 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140213532-A1 COMPOSITIONS AND METHODS FOR ENHANCING DRUG DELIVERY ACROSS AND INTO EPITHELIAL TISSUES KAI PHARMACEUTICALS, INC. (US) 2014-07-31 US disclosed
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed
US-20070015818-A1 Cyclic sulfone containing retroviral protease inhibitors G.D. Searle & Co. (now G.D. Searle, LLC) (US) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213532-A1 COMPOSITIONS AND METHODS FOR ENHANCING DRUG DELIVERY ACROSS AND INTO EPITHELIAL TISSUES ADM2, SLC7A1, ARG1 HTT 1251/4885KMT2A 3688/4885CAD 700/4885
US-20070015818-A1 Cyclic sulfone containing retroviral protease inhibitors TMPRSS15, TMPRSS11D, MME HTT 1976/4885KMT2A 1138/4885CAD 2131/4885
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 HTT 1056/4885KMT2A 4420/4885CAD 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.