Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288851 | 0.93 | FAAH (0.60) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL4183181 | 0.85 | FAAH (0.71) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL14288743 | 0.84 | FAAH (0.50) | FAAHALDH1A1TRPA1EPHX2FAAH2 | |
| SCHEMBL4181464 | 0.81 | RAB9A (0.60) | ALDH1A1RAB9A | |
| SCHEMBL4965649 | 0.81 | FAAH (0.66) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL4750537 | 0.81 | FAAH (0.86) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL4751725 | 0.80 | FAAH (0.65) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL4748396 | 0.79 | FAAH (0.62) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL14470485 | 0.78 | FAAH (0.62) | FAAHALDH1A1RAB9ATRPA1EPHX2 | |
| SCHEMBL21618461 | 0.77 | ALDH1A1 (1.00) | FAAHALDH1A1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020866-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON | 2008-02-21 | — | — | WO | disclosed |
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, NAAA | FAAH 1/4885ALDH1A1 366/4885RAB9A 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.