Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.66 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.66 |
| ▸ | MGLL | Q99685 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751725 | 0.88 | FAAH (0.65) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL4183181 | 0.88 | FAAH (0.71) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL4748396 | 0.86 | FAAH (0.62) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL4750537 | 0.86 | FAAH (0.86) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL14470485 | 0.86 | FAAH (0.62) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL14199506 | 0.84 | FAAH (0.63) | FAAHALDH1A1RAB9AEPHX1 | |
| SCHEMBL14044821 | 0.82 | FAAH (0.67) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL14288607 | 0.81 | FAAH (0.62) | FAAHTRPA1EPHX2FAAH2MGLL | |
| SCHEMBL4966297 | 0.81 | ALDH1A1 (0.55) | FAAHHDAC6ALDH1A1 | |
| SCHEMBL11869659 | 0.80 | RAB9A (0.58) | FAAHALDH1A1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351495-A | fatty acid amide hydrolase inhibitors | ORGANON NV (NL) | 2009-01-21 | — | — | CN | disclosed |
| EP-1969051-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2008-09-17 | — | — | EP | disclosed |
| WO-2008024139-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007079180-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155747-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070155747-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155747-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ABHD6 | FAAH 1/4885TRPA1 1100/4885EPHX2 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.