Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288649 | 0.93 | CTSK (0.56) | CTSKCTSLCTSBCTSSCASP1 | |
| SCHEMBL8289708 | 0.91 | CTSL (0.52) | CTSKCTSLCTSBCTSSCASP1 | |
| SCHEMBL14288670 | 0.90 | CTSK (0.50) | CTSKCTSLCTSBCTSS | |
| SCHEMBL5491311 | 0.82 | CASP3 (0.50) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL5496674 | 0.82 | CASP3 (0.50) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL5496679 | 0.82 | CASP3 (0.50) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL7331686 | 0.77 | CTSK (0.65) | CTSKCTSLCTSBCTSSCASP1 | |
| SCHEMBL7299710 | 0.77 | CTSK (0.65) | CTSKCTSLCTSBCTSSCASP1 | |
| SCHEMBL15649130 | 0.76 | CTSK (0.60) | CTSKCTSLCTSBCTSSCASP1 | |
| SCHEMBL25282430 | 0.76 | CTSK (0.65) | CTSKCTSLCTSBCTSSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021025-A1 | INHIBITORS OF CATHEPSIN S | LIU HONG | 2008-01-24 | — | — | US | disclosed |
| US-7297714-B2 | Selective in presence of at least one other cathepsin isozyme; such as (3-cyclopentyl-{[5-(3-fluoro-phenyl)-furan-2-carbonyl]-amino}-propionylamino)-4-oxo-butyric acid | IRM LLC (BM) | 2007-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021025-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSB, CTSZ | CTSK 9/4885CTSL 11/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.