SCHEMBL142925

SCHEMBL142925

CCN(CC)CCN1c2ccccc2Sc2ccc(Cl)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 1/20 0.76
ICAM1 P05362 1/20 0.76
ITGAL P20701 1/20 0.76
CYP1A2 P05177 4/20 0.69
CYP2D6 P10635 4/20 0.69
MAPT P10636 4/20 0.69
CYP2C19 P33261 4/20 0.69
LMNA P02545 3/20 0.69
HTR1A P08908 3/20 0.69
DRD2 P14416 3/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
CYP3A4 P08684 3/20 0.69
TDP1 Q9NUW8 2/20 0.69
SLC22A1 O15245 2/20 0.69
ABCB11 O95342 2/20 0.69
TP53 P04637 2/20 0.69
FYN P06241 2/20 0.69
CHRM2 P08172 2/20 0.69
CHRM4 P08173 2/20 0.69
CHRM5 P08912 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7342890 0.99 ITGB2 (0.74) ITGB2ICAM1ITGALCYP1A2CYP2D6
Chlorproethazine SCHEMBL29818123 0.92 CYP1A2 (0.77) ITGB2ICAM1ITGALCYP1A2CYP2D6
Chlorproethazine SCHEMBL149201 0.92 CYP1A2 (0.77) ITGB2ICAM1ITGALCYP1A2CYP2D6
Chlorproethazine SCHEMBL9724486 0.91 LMNA (0.78) ITGB2ICAM1ITGALCYP1A2CYP2D6
Chlorproethazine SCHEMBL1648952 0.90 CYP1A2 (0.74) ITGB2ICAM1ITGALCYP1A2CYP2D6
Diethazine SCHEMBL142924 0.87 POLB (0.83) ITGB2ICAM1ITGALCYP1A2CYP2D6
Diethazine SCHEMBL30592079 0.87 POLB (0.83) ITGB2ICAM1ITGALCYP1A2CYP2D6
Cholrphenethazine SCHEMBL3456873 0.86 ITGB2 (1.00) ITGB2ICAM1ITGALCYP1A2CYP2D6
Diethazine SCHEMBL142381 0.86 POLB (0.81) ITGB2ICAM1ITGALCYP1A2CYP2D6
SCHEMBL7347822 0.86 ITGB2 (0.60) ITGB2ICAM1ITGALCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1273301-B1 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON SA (CH) 2006-09-06 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors REGENERON PHARMA (US) 2026-04-09 US disclosed
US-12472241-B2 Treatment of respiratory disorders with arachidonate 15-lipoxygenase (ALOX15) inhibitors REGENERON PHARMACEUTICALS, INC. (US) 2025-11-18 US disclosed
US-20250288591-A1 TRIMEPRAZINE FOR USE IN TREATING TRIGEMINAL NEURALGIA AND FOR REDUCING PAIN RELATED THERETO UNDAUNTED BIO, INC. (US) 2025-09-18 US disclosed
US-20250134903-A1 COMPOSITIONS AND METHODS FOR TREATING PAIN UNDAUNTED BIO, INC. (US) 2025-05-01 US disclosed
US-20250082647-A1 SPECIFIC DOSAGE OF PHENOTHIAZINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF ALZHEIMER'S DEMENTIA IMMUNGENETICS AG (DE) 2025-03-13 US disclosed
US-20240277756-A1 SILICON PARTICLES FOR HYDROGEN RELEASE NACAMED AS (NO) 2024-08-22 US disclosed
CN-118510519-A Specific doses of phenothiazine compounds for use in the treatment or prevention of Alzheimer's dementia 免疫基因股份公司 2024-08-16 CN disclosed
US-20240189234-A1 SILICON PARTICLES FOR DRUG DELIVERY NACAMED AS (NO) 2024-06-13 US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
EP-0737066-A1 TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER NOVEN PHARMACEUTICALS, INC. (US) 1996-10-16 EP disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed
WO-1995018603-A1 TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER NOVEN PHARMACEUTICALS, INC. (US) 1995-07-13 WO disclosed
US-4201725-A TRISUBSTITUTED METHYL-N-METHYLAMINE, PARKINSON*S DISEASE, ANTISPASMODIC AGENTS LABAZ (FR) 1980-05-06 US disclosed
US-4057644-A PARKINSON'S DISEASE LABAZ (FR) 1977-11-08 US disclosed
US-4048334-A PARKINSON*S DISEASE, NEUROLEPTIC AGENTS LABAZ (FR) 1977-09-13 US disclosed
US-4026925-A PARKINSON*S DISEASE LABAZ (FR) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082647-A1 SPECIFIC DOSAGE OF PHENOTHIAZINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF ALZHEIMER'S DEMENTIA PSEN1, PSEN2, APP ITGB2 2928/4885ICAM1 887/4885ITGAL 2688/4885
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors ALOX15, ALOX15B, ALOX5 ITGB2 4795/4885ICAM1 1916/4885ITGAL 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.