SCHEMBL14295232

SCHEMBL14295232

CC(C)c1ccc2c(c1)sc1ccc3ccccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
SCN4A P35499 1/20 0.39
HSD17B10 Q99714 3/20 0.38
AKR1B1 P15121 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
HIF1A Q16665 2/20 0.38
UGT2B7 P16662 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
ATM Q13315 1/20 0.38
NQO1 P15559 1/20 0.36
NQO2 P16083 1/20 0.36
PRNP P04156 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14295230 0.89 UGT2B7 (0.39) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL13506886 0.85 RAB9A (0.42) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL15852595 0.83 AKR1B1 (0.34) KIF11RAB9AHSD17B10AKR1B1L3MBTL1
SCHEMBL23775990 0.80 KIF11 (0.41) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL14133036 0.80 RAB9A (0.44) KIF11RAB9ASMN1; SMN2NPC1HSD17B10
SCHEMBL13338346 0.79 GPR3 (0.54) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL14295231 0.78 RAB9A (0.42) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL13506646 0.78 KIF11 (0.45) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL26415756 0.77 AKR1C3 (0.37) KIF11RAB9ASMN1; SMN2NPC1SCN4A
SCHEMBL17275796 0.76 CYP2A6 (0.42) RAB9ASMN1; SMN2HSD17B10L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023243925-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-12-21 WO disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 US disclosed
US-20210253586-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-08-19 US disclosed
EP-3541890-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-28 EP disclosed
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-12-20 US disclosed
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME INMT, TYR, ALKBH2 KIF11 2179/4885RAB9A 4311/4885SMN1; SMN2 3384/4885
US-20210253586-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, RIF1 KIF11 3394/4885RAB9A 2543/4885SMN1; SMN2 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.