Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343522 | 0.74 | NR1D1 (0.50) | NR1D1TP53 | |
| SCHEMBL4959583 | 0.74 | NR1D1 (0.50) | NR1D1TP53 | |
| SCHEMBL15536062 | 0.73 | ACHE (0.42) | KCNH2MAPTKMT2AMEN1CCR8 | |
| SCHEMBL9867636 | 0.70 | ALDH1A1 (0.51) | NR1D1TP53MAPTSMN1; SMN2 | |
| SCHEMBL16879293 | 0.69 | NR1D1 (0.59) | NR1D1POLB | |
| SCHEMBL10424610 | 0.69 | NR1D1 (0.47) | NR1D1MAPTKMT2A | |
| SCHEMBL9866691 | 0.68 | LTA4H (0.47) | NR1D1KMT2AMEN1 | |
| SCHEMBL5706020 | 0.67 | SLC6A3 (0.69) | MAPTKMT2ASMN1; SMN2SLC6A3 | |
| SCHEMBL10906109 | 0.67 | NR1D1 (0.51) | NR1D1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10385107 | 0.66 | NR1D1 (0.47) | NR1D1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335657-B2 | Cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |