Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 10/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313417 | 0.86 | MET (0.39) | METHPGDSWNT3A | |
| SCHEMBL3219716 | 0.85 | GRIN2B (0.41) | GRIN2BHPGDSCYP1A2CYP3A4WNT3A | |
| SCHEMBL14313134 | 0.85 | HPGDS (0.41) | GRIN2BMETHPGDSWNT3A | |
| SCHEMBL14312791 | 0.85 | NR3C2 (0.36) | GRIN2BMETHPGDSWNT3A | |
| SCHEMBL14312890 | 0.84 | SLC22A12 (0.37) | METHPGDSWNT3ABCHEACHE | |
| SCHEMBL14312729 | 0.84 | MET (0.39) | GRIN2BMETHPGDSWNT3A | |
| SCHEMBL14312803 | 0.78 | MET (0.39) | METHPGDS | |
| SCHEMBL14312907 | 0.78 | PTGS2 (0.39) | METHPGDS | |
| SCHEMBL3213787 | 0.78 | HPGDS (0.56) | GRIN2BHPGDSCYP1A2CYP3A4WNT3A | |
| SCHEMBL14313117 | 0.76 | HPGDS (0.38) | GRIN2BMETHPGDSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |