Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433055 | 0.90 | KMT2A (0.43) | TACR1KMT2AXIAPAADAT | |
| SCHEMBL1432319 | 0.90 | KMT2A (0.43) | TACR1KMT2AXIAPAADAT | |
| SCHEMBL1432803 | 0.89 | CTSB (0.41) | KMT2ACTSL | |
| SCHEMBL1432409 | 0.88 | CTSL (0.48) | F2CTSL | |
| SCHEMBL1432148 | 0.88 | KMT2A (0.43) | KMT2ATSHR | |
| SCHEMBL1432180 | 0.87 | DPP4 (0.40) | KMT2AXIAP | |
| SCHEMBL1431638 | 0.87 | DPP4 (0.40) | KMT2AXIAP | |
| Hydrochloric Acid SCHEMBL1432515 | 0.86 | DPP4 (0.40) | KMT2AXIAP | |
| SCHEMBL1432452 | 0.86 | TLR2 (0.42) | TACR1KMT2AAADAT | |
| SCHEMBL1432690 | 0.86 | TLR2 (0.42) | TACR1KMT2AAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |