Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 16/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431988 | 0.90 | TACR1 (0.44) | — | |
| SCHEMBL1432571 | 0.90 | LCK (0.41) | — | |
| SCHEMBL1432409 | 0.88 | CTSL (0.48) | — | |
| SCHEMBL1431568 | 0.88 | TACR1 (0.44) | EPHX2P2RX7 | |
| SCHEMBL1431638 | 0.85 | DPP4 (0.40) | ALDH1A1 | |
| SCHEMBL1432180 | 0.85 | DPP4 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1432515 | 0.85 | DPP4 (0.40) | ALDH1A1 | |
| SCHEMBL1432824 | 0.84 | MASP2 (0.41) | — | |
| SCHEMBL1433133 | 0.84 | TACR1 (0.43) | — | |
| SCHEMBL1432690 | 0.84 | TLR2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |