Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327783 | 0.90 | MEN1 (0.47) | GPR84MEN1KMT2AGAAPOLB | |
| SCHEMBL14327784 | 0.81 | HSP90AA1 (0.48) | GPR84MEN1KMT2AGAAPOLB | |
| SCHEMBL22229788 | 0.80 | GPR84 (0.48) | GPR84MEN1KMT2AGAAPOLB | |
| SCHEMBL14327790 | 0.80 | GPR84 (0.43) | GPR84MEN1KMT2AGAAPOLB | |
| SCHEMBL12786270 | 0.79 | NQO1 (0.46) | GPR84MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL340013 | 0.76 | ALDH1A1 (0.73) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL31411213 | 0.76 | ALDH1A1 (0.73) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL14327767 | 0.76 | CA2 (0.47) | GPR84MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14327801 | 0.76 | GPR84 (0.47) | GPR84MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL14327802 | 0.75 | ALOX5 (0.51) | GPR84MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420847-B2 | Bis-phosphate compound and asymmetric reaction using the same | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420847-B2 | Bis-phosphate compound and asymmetric reaction using the same | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | API CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | AASDHPPT, ALDH7A1, ATIC | GPR84 2802/4885MEN1 1325/4885KMT2A 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.