Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432117 | 0.88 | F2R (0.35) | MASP2S1PR3TRPV1FURINF2R | |
| SCHEMBL1432274 | 0.79 | AAK1 (0.38) | MASP2S1PR3FURINAAK1HDAC1 | |
| SCHEMBL1432596 | 0.78 | MASP2 (0.39) | MASP2FURINTSHRF2R | |
| SCHEMBL1902789 | 0.78 | NAMPT (0.44) | MASP2AAK1HDAC1 | |
| SCHEMBL1901816 | 0.77 | MASP2 (0.39) | MASP2FURINCYP3A4TSHRF2R | |
| SCHEMBL1432473 | 0.76 | MASP2 (0.38) | MASP2FURINCYP3A4TSHR | |
| SCHEMBL1904795 | 0.76 | S1PR3 (0.39) | S1PR3TRPV1AAK1 | |
| SCHEMBL1433593 | 0.75 | MASP2 (0.35) | MASP2FURINCYP3A4CA1CA2 | |
| SCHEMBL1432283 | 0.75 | ALDH1A1 (0.49) | F2R | |
| SCHEMBL1432104 | 0.73 | CYP3A4 (0.38) | MASP2CYP3A4CA1CA2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |