Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431222 | 0.93 | RXFP1 (0.71) | RXFP1MEN1KMT2AMAPTTRPM2 | |
| SCHEMBL14340794 | 0.88 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL27546747 | 0.81 | HCAR2 (0.60) | RXFP1MEN1KMT2AMAPTGRIK1 | |
| SCHEMBL15530093 | 0.79 | RXFP1 (1.00) | RXFP1PPARGPPARDPPARANR1H4 | |
| SCHEMBL4040223 | 0.78 | ALDH1A1 (0.82) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL5696444 | 0.77 | ALDH1A1 (0.68) | RXFP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14150074 | 0.77 | MEN1 (0.57) | RXFP1MEN1KMT2AMAPTTRPM2 | |
| SCHEMBL14340789 | 0.77 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL23296145 | 0.77 | RXRA (0.58) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8437112 | 0.77 | ALDH1A1 (0.79) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2007-12-06 | — | — | US | disclosed |
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281969-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | GPR119, FFAR1, HCAR1 | RXFP1 730/4885MEN1 2134/4885KMT2A 3675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.