Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | LGMN | Q99538 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17642581 | 0.92 | AKR1C3 (0.57) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2883585 | 0.88 | LTA4H (0.67) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL9093746 | 0.87 | LMNA (0.71) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14345952 | 0.85 | AKR1C3 (0.57) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL18815076 | 0.80 | LTA4H (0.52) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2175616 | 0.80 | LMNA (0.62) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL625677 | 0.80 | ALDH1A1 (0.54) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28298610 | 0.78 | AKR1C3 (0.45) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL14862707 | 0.78 | AKR1C3 (0.49) | AKR1C3LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL133561 | 0.78 | ALDH1A1 (0.58) | AKR1C3LMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421243-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) | 2025-09-23 | — | — | US | disclosed |
| EP-4570317-A2 | COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | Intervet International B.V. (NL) | 2025-06-18 | — | — | EP | disclosed |
| US-20240425504-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) | 2024-12-26 | — | — | US | disclosed |
| EP-3808747-B1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL (JP) | 2024-12-18 | — | — | EP | disclosed |
| US-12077531-B2 | Imidazopyridinone compound | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2024-09-03 | — | — | US | disclosed |
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2024-08-15 | — | — | US | disclosed |
| EP-4370111-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2024-05-22 | — | — | EP | disclosed |
| CN-117924285-A | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) | 2023-12-19 | — | — | US | disclosed |
| EP-4276102-A2 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | Printnet Kereskedelmi és Szolgáltató Kft. (HU) | 2023-11-15 | — | — | EP | disclosed |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| WO-2010088574-A1 | AZABENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20100093703-A1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |
| EP-2121600-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | Boehringer Ingelheim International GmbH (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099000-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | disclosed |
| CN-1349498-A | Alkenyl-and alkynyl-containing metalloprotease inhibitors | PROCTER & GAMBLE (US) | 2002-05-15 | — | — | CN | disclosed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | AKR1C3 3450/4885LMNA 1262/4885MAPT 99/4885 |
| US-20100093703-A1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | PYGL, PYGM, G6PC1 | AKR1C3 2069/4885LMNA 1244/4885MAPT 947/4885 |
| US-12077531-B2 | Imidazopyridinone compound | EGLN3, DHPS, EGLN2 | AKR1C3 381/4885LMNA 4743/4885MAPT 4146/4885 |
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | AKR1C3 3450/4885LMNA 1262/4885MAPT 99/4885 |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | VAPB, VAPA, BET1 | AKR1C3 3552/4885LMNA 3869/4885MAPT 1522/4885 |
| US-20240425504-A1 | IMIDAZOPYRIDINONE COMPOUND | EGLN3, DHPS, EGLN2 | AKR1C3 381/4885LMNA 4743/4885MAPT 4146/4885 |
| US-12421243-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | AKR1C3 3450/4885LMNA 1262/4885MAPT 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.