SCHEMBL14356142

SCHEMBL14356142

CCCCc1ccc(-c2ccc(OCC)c(F)c2F)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 2/20 0.47
CTSK P43235 2/20 0.47
CTSL P07711 1/20 0.47
TYR P14679 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
ELANE P08246 1/20 0.34
CTSG P08311 1/20 0.34
FGFR2 P21802 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
FGFR1 P11362 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12238352 0.93 TYR (0.42) CTSSCTSKCTSLTYRL3MBTL1
SCHEMBL12579513 0.90 CTSS (0.56) CTSSCTSKCTSLL3MBTL1ELANE
SCHEMBL427589 0.87 CTSL (0.40) CTSSCTSKCTSLTYRL3MBTL1
SCHEMBL10302840 0.87 CTSL (0.40) CTSSCTSKCTSLTYRL3MBTL1
SCHEMBL18136390 0.87 ALOX5 (0.45) CTSSCTSKCTSLTYRL3MBTL1
SCHEMBL17108406 0.86 TYR (0.47) CTSSCTSKCTSLTYRELANE
SCHEMBL16852409 0.84 NAAA (0.42) CTSSCTSKCTSLTYRL3MBTL1
SCHEMBL9978960 0.84 CTSS (0.44) CTSSCTSKCTSLL3MBTL1FGFR2
SCHEMBL13243902 0.83 CTSS (0.44) CTSSCTSKCTSLL3MBTL1FGFR2
SCHEMBL29444864 0.83 L3MBTL1 (0.47) L3MBTL1FGFR2FGFR1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294371-B2 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-13 US disclosed
US-7294371-B2 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-13 US disclosed