SCHEMBL3001679

SCHEMBL3001679

O=C(CCCN1C(=O)C2=C(CCCC2)C1=O)OO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KMT2A Q03164 4/20 0.40
HSD17B10 Q99714 3/20 0.40
MEN1 O00255 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
ACHE P22303 1/20 0.36
MAPT P10636 4/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 2/20 0.34
HPGD P15428 2/20 0.34
HTR7 P34969 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
RECQL P46063 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7802057 0.81 MEN1 (0.47) ALDH1A1KMT2AHSD17B10MEN1ACHE
SCHEMBL7796004 0.79 SMN1; SMN2 (0.44) ALDH1A1KMT2AHSD17B10MEN1MAPT
SCHEMBL15998790 0.79 TSHR (0.40) ALDH1A1HSD17B10TDP1MAPTLMNA
SCHEMBL10908051 0.76 HTR7 (0.43) ALDH1A1KMT2AMEN1TDP1MAPT
SCHEMBL7796009 0.75 HTT (0.47) ALDH1A1KMT2AMEN1TDP1MAPK1
SCHEMBL7802815 0.75 HTT (0.47) ALDH1A1KMT2AMEN1TDP1MAPK1
SCHEMBL134590 0.73 KMT2A (0.68) ALDH1A1KMT2AHSD17B10MEN1TDP1
SCHEMBL10430582 0.73 HTT (0.44) ALDH1A1KMT2ASMN1; SMN2L3MBTL1RAB9A
SCHEMBL24939775 0.73 ALDH1A1 (0.57) ALDH1A1KMT2AHSD17B10MEN1ALOX15
SCHEMBL8338284 0.72 SMN1; SMN2 (0.52) ALDH1A1KMT2AHSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER L'OREAL (FR) 2009-11-05 US claimed
EP-0366041-B2 Imido-percarboxylic acids AUSIMONT SPA (IT) 2001-09-12 EP claimed
EP-0366041-B1 Imido-percarboxylic acids AUSIMONT SPA (IT) 1998-08-05 EP claimed
US-5536434-A BLEACHES AUSIMONT S.P.A. (IT) 1996-07-16 US claimed
EP-0366041-A2 Imido-percarboxylic acids AUSIMONT S.r.l. (IT) 1990-05-02 EP claimed
US-20100189675-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'OREAL (FR) 2010-07-29 US disclosed
EP-2157964-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'Oreal (FR) 2010-03-03 EP disclosed
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER L'OREAL (FR) 2009-11-05 US disclosed
WO-2009001296-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT L'OREAL (FR) 2008-12-31 WO disclosed
EP-0366041-B2 Imido-percarboxylic acids AUSIMONT SPA (IT) 2001-09-12 EP disclosed
EP-0366041-B1 Imido-percarboxylic acids AUSIMONT SPA (IT) 1998-08-05 EP disclosed
US-5536434-A BLEACHES AUSIMONT S.P.A. (IT) 1996-07-16 US disclosed
EP-0366041-A2 Imido-percarboxylic acids AUSIMONT S.r.l. (IT) 1990-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189675-A1 COSMETIC USE OF AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AS DESQUAMATING AGENT NISCH, CUTA, DDC ALDH1A1 1251/4885KMT2A 4078/4885HSD17B10 2657/4885
US-20090275630-A1 COSMETIC COMPOSITION COMPRISING AN IMIDOPERCARBOXYLIC ACID DERIVATIVE AND A N-ACYLATED AMINO ACID ESTER DDC, ALAD, AADAC ALDH1A1 407/4885KMT2A 2231/4885HSD17B10 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.