Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586107 | 0.82 | CA2 (0.68) | CA1CA2CA9TDP1 | |
| SCHEMBL1162017 | 0.80 | CHRNA7 (0.49) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL1772727 | 0.79 | TBXAS1 (0.43) | CHRNA7TBXAS1FDPSCYP2A6NAPRT | |
| SCHEMBL28017528 | 0.79 | NAMPT (0.48) | CA1CA2CHRNA7TBXAS1CA9 | |
| SCHEMBL14716358 | 0.78 | CA2 (0.55) | CA1CA2CA9 | |
| SCHEMBL2148560 | 0.76 | FDPS (0.43) | TBXAS1FDPSNAPRT | |
| SCHEMBL27807750 | 0.74 | TBXAS1 (0.42) | TBXAS1FDPSTDP1 | |
| SCHEMBL26860610 | 0.73 | CHRNA7 (0.57) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL3890904 | 0.73 | CA2 (0.56) | CA1CA2CA9 | |
| SCHEMBL9572659 | 0.73 | TAAR1 (0.53) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723727-B1 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | SHAN DONG LUYE PHARM CO LTD (CN) | 2017-03-01 | — | — | EP | disclosed |
| US-8809590-B2 | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol | SHAN DONG LUYE PHARMACEUTICAL CO., LTD. (CN) | 2014-08-19 | — | — | US | disclosed |
| CN-103649071-B | Industrial preparation method of nitrogen-substituted amino 5,6,7, 8-tetrahydronaphthol | SHANDONG LVYE PHARMACEUTICAL CO LTD | 2014-07-30 | — | — | CN | disclosed |
| US-20140121380-A1 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | SHAN DONG LUYE PHARMACEUTICAL CO., LTD. (CN) | 2014-05-01 | — | — | US | disclosed |
| EP-2723727-A1 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | Shan Dong Luye Pharmaceutical Co., Ltd. (CN) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013000273-A1 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | SHAN DONG LUYE PHARMACEUTICAL CO., LTD. (CN) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121380-A1 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | AASDHPPT, DOHH, DNPH1 | CA1 1134/4885CA2 1291/4885CHRNA7 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.