SCHEMBL143628

SCHEMBL143628

Clc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
AHR P35869 1/20 0.41
HSP90AA1 P07900 2/20 0.41
HSP90AB1 P08238 2/20 0.41
HTR2B P41595 1/20 0.41
PDE4D Q08499 1/20 0.41
HSD11B1 P28845 1/20 0.41
GRM5 P41594 1/20 0.40
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MGAM O43451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401780 1.00 CYP3A4 (0.44) CYP3A4TSHRMAPK1TDP1AHR
SCHEMBL7757952 0.83 DPP4 (0.54) MAPK1TDP1LMNAMAPTSMN1; SMN2
SCHEMBL1131300 0.79 MEN1 (0.45) CYP3A4MAPK1TDP1HSP90AA1GRM5
SCHEMBL10642190 0.76 AHR (0.47) AHRHSP90AA1HSP90AB1HTR2BPDE4D
SCHEMBL5147046 0.75
SCHEMBL389207 0.74 EGFR (0.34) MEN1MAPTKMT2ACRHR1
SCHEMBL5147049 0.74
SCHEMBL392325 0.74 CNR2 (0.33) MAPTRAB9AALDH1A1CNR1CNR2
SCHEMBL4578554 0.74
SCHEMBL9566485 0.73 HTR2B (0.72) CYP3A4TSHRAHRHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049481-A Merocyanine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US claimed
US-4239850-A PHOTOINITIATOR OF AN UNSATURATED KETONE AND A TRIHALOMETHYL TRIAZINE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE KURARAY NORITAKE DENTAL INC. (JP) 2025-06-26 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-3542775-B1 COMPOSITION WITH EXCELLENT STORAGE STABILITY USING HIGHLY BASIC FILLER SHOFU INC (JP) 2025-04-02 EP disclosed
US-20250057733-A1 CURABLE DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
US-20250057732-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
US-4937161-A INITIATOR COMBINATION OF ORGANIC BORON COMPOUND ANION SALT OF ORGANIC CATIONIC DYE AND TRIAZINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-06-26 US disclosed
US-4935330-A Photopolymerizable mixture, photosensitive recording element containing this mixture, and the production of lithographic printing plate using this photosensitive recording element BASF AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed
US-4877711-A DURABLE PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4810618-A HIGH SENSITIVITY, PRINTING PLATES, PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1989-03-07 US disclosed
US-4774163-A LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1988-09-27 US disclosed
EP-0234570-A2 Photopolymerizable composition, photosensitive element with that composition, and process for the production of a lithographic printing plate using this element BASF Aktiengesellschaft (DE) 1987-09-02 EP disclosed
US-4505793-A INITIATOR IS BLEND OF 3-KETO-SUBSTITUTED CUMARIN AND HALOGEN COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US disclosed
US-4258123-A UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4239850-A PHOTOINITIATOR OF AN UNSATURATED KETONE AND A TRIHALOMETHYL TRIAZINE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A CYP3A4 3149/4885TSHR 4128/4885MAPK1 4610/4885
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE ACR, CAD, ALG3 CYP3A4 3827/4885TSHR 4860/4885MAPK1 2373/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 CYP3A4 2289/4885TSHR 3780/4885MAPK1 2296/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL CYP3A4 2922/4885TSHR 4185/4885MAPK1 2713/4885
US-20250057732-A1 DENTAL CURABLE COMPOSITION CAD, MMAB, DNMT3L CYP3A4 3345/4885TSHR 4445/4885MAPK1 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.