SCHEMBL29401780

SCHEMBL29401780

Clc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
AHR P35869 1/20 0.41
HSP90AA1 P07900 2/20 0.41
HSP90AB1 P08238 2/20 0.41
HTR2B P41595 1/20 0.41
PDE4D Q08499 1/20 0.41
HSD11B1 P28845 1/20 0.41
GRM5 P41594 1/20 0.40
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MGAM O43451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143628 1.00 CYP3A4 (0.44) CYP3A4TSHRMAPK1TDP1AHR
SCHEMBL7757952 0.83 DPP4 (0.54) MAPK1TDP1LMNAMAPTSMN1; SMN2
SCHEMBL1131300 0.79 MEN1 (0.45) CYP3A4MAPK1TDP1HSP90AA1GRM5
SCHEMBL10642190 0.76 AHR (0.47) AHRHSP90AA1HSP90AB1HTR2BPDE4D
SCHEMBL5147046 0.75
SCHEMBL389207 0.74 EGFR (0.34) MEN1MAPTKMT2ACRHR1
SCHEMBL5147049 0.74
SCHEMBL392325 0.74 CNR2 (0.33) MAPTRAB9AALDH1A1CNR1CNR2
SCHEMBL4578554 0.74
SCHEMBL9566485 0.73 HTR2B (0.72) CYP3A4TSHRAHRHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER SHOFU INC (JP) 2025-02-27 US disclosed
CN-112771057-B Free radical polymerizable silane coupling compound with urethane bond based on diisocyanate 株式会社松风 2024-12-20 CN disclosed
EP-4473954-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER Shofu Inc. (JP) 2024-12-11 EP disclosed
CN-119074563-A Dental curable composition containing ultraviolet absorber 株式会社松风 2024-12-06 CN disclosed
CN-113402666-B Dental photocurable composition excellent in color tone selectivity 株式会社松风 2024-11-15 CN disclosed
CN-113402665-B Dental photocurable composition comprising a highly soluble photoacid generator 株式会社松风 2024-11-15 CN disclosed
CN-118946340-A Curable composition for dentistry having excellent color tone adaptability 可乐丽则武齿科株式会社 2024-11-12 CN disclosed
CN-118922164-A Adhesive composition for both light-molded article and non-light-molded article 可乐丽则武齿科株式会社 2024-11-08 CN disclosed
US-12064493-B2 Dental photocurable composition having excellent storage stability SHOFU INC. (JP) 2024-08-20 US disclosed
CN-115068347-A Photocurable composition having excellent depth of cure 株式会社松风 2022-09-20 CN disclosed
US-20220287918-A1 DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY SHOFU INC. (JP) 2022-09-15 US disclosed
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH SHOFU INC. (JP) 2022-09-15 US disclosed
US-20220287921-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN COLOR TONE SELECTIVITY SHOFU INC. (JP) 2022-09-15 US disclosed
US-20220287920-A1 DENTAL PHOTOCURABLE COMPOSITION CONTAINING HIGH SOLUBLE PHOTOACID GENERATOR SHOFU INC. (JP) 2022-09-15 US disclosed
EP-4056163-A1 DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY Shofu Inc. (JP) 2022-09-14 EP disclosed
EP-4056164-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH Shofu Inc. (JP) 2022-09-14 EP disclosed
CN-114828803-A Dental restorative composition 可乐丽则武齿科株式会社 2022-07-29 CN disclosed
WO-2022092193-A1 DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY クラレノリタケデンタル株式会社 2022-05-05 WO disclosed
CN-109890344-B Subpackaged dental adhesive 可乐丽则武齿科株式会社 2022-02-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 CYP3A4 4813/4885TSHR 3276/4885MAPK1 1452/4885
US-12064493-B2 Dental photocurable composition having excellent storage stability H1-0, H1-2, H1-4 CYP3A4 4734/4885TSHR 3869/4885MAPK1 869/4885
US-20220287920-A1 DENTAL PHOTOCURABLE COMPOSITION CONTAINING HIGH SOLUBLE PHOTOACID GENERATOR AP2S1, AP3S1, ASIC1 CYP3A4 3853/4885TSHR 3768/4885MAPK1 1002/4885
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER ERCC1, DSC1, CRYAA CYP3A4 1960/4885TSHR 4039/4885MAPK1 4444/4885
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH ODC1, AOC2, CCNT1 CYP3A4 2731/4885TSHR 4012/4885MAPK1 1293/4885
US-20220287921-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN COLOR TONE SELECTIVITY HBG1, MARK1, KATNA1 CYP3A4 3979/4885TSHR 4542/4885MAPK1 500/4885
US-20220287918-A1 DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY ITGA1, ITGB1, CDH1 CYP3A4 4457/4885TSHR 3917/4885MAPK1 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.