SCHEMBL14363642

SCHEMBL14363642

Cc1ccc(S(=O)(=O)OCCCN=[N+]=[N-])cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
PSMD10 O75832 1/20 0.39
CYP24A1 Q07973 2/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
STAT3 P40763 1/20 0.38
GAA P10253 1/20 0.37
G6PD P11413 1/20 0.37
VDR P11473 1/20 0.36
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16599488 0.95 CA12 (0.39) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL26634633 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL21179227 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL18301202 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL15881370 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL31556805 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL31556837 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL13884657 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL15264830 0.94 CA12 (0.38) CA12CA1CA9ALDH1A1CYP3A4
SCHEMBL26049382 0.91 ALDH1A1 (0.40) CA12CA1CA9ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176793-A Synthesis method and application of targeted degradation chimeric 西华大学 2024-12-24 CN claimed
US-20250236607-A1 CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF OHIO STATE INNOVATION FOUNDATION 2025-07-24 US disclosed
EP-4561585-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS FOR USE IN THE TREATMENT, INHIBITION OF PROGRESSION, AND PREVENTION OF ECTOPIC CALCIFICATION Sanifit Therapeutics S.A. (ES) 2025-06-04 EP disclosed
EP-4562019-A1 IP5 SUBSTITUTED COMPOUNDS Sanifit Therapeutics S.A. (ES) 2025-06-04 EP disclosed
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2025-05-29 US disclosed
CN-119855595-A IP4-4,6 substituted derivative compounds for treating ectopic calcification, inhibiting progression and preventing ectopic calcification 萨尼菲特治疗有限公司 2025-04-18 CN disclosed
EP-4536668-A1 PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS KRAS INHIBITORS Bristol-Myers Squibb Company (US) 2025-04-16 EP disclosed
WO-2025075958-A1 POLYMER-FUNCTIONALIZED RETICULAR MATERIALS FOR CARBON DIOXIDE CAPTURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-10 WO disclosed
CN-119630679-A IP5 substituted compounds 萨尼菲特治疗有限公司 2025-03-14 CN disclosed
CN-119630676-A Pyrido [4,3-D ] pyrimidine derivatives as KRAS inhibitors 百时美施贵宝公司 2025-03-14 CN disclosed
US-20140066576-A1 SWITCHABLE IONIC ADHESIVE COATING FOR RECYCLABLE CARBON FIBER EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-03-06 US disclosed
US-20140066576-A1 SWITCHABLE IONIC ADHESIVE COATING FOR RECYCLABLE CARBON FIBER EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-03-06 US disclosed
CN-101679430-B 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of ORL-i receptor for treatment of anxiety and depression JANSSEN PHARMACEUTICA NV 2013-12-25 CN disclosed
US-20120028249-A1 ANTHRAQUINONE BASED NEAR IR EMITTING COMPOUNDS AND USES THEREOF Life Technologies Corporation (US) 2012-02-02 US disclosed
US-20120028249-A1 ANTHRAQUINONE BASED NEAR IR EMITTING COMPOUNDS AND USES THEREOF Life Technologies Corporation (US) 2012-02-02 US disclosed
US-20100247439-A1 DENDRITIC NANO-ANTIOXIDANTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-09-30 US disclosed
CN-101679430-A 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-i receptor for the treatment of anxiety and depression JANSSEN PHARMACEUTICA NV 2010-03-24 CN disclosed
EP-1862466-A2 Arrays with cleavable linkers The Scripps Research Institute (US) 2007-12-05 EP disclosed
US-20070213278-A1 Arrays with cleavable linkers SCRIPPS RESEARCH INSTITUTE, THE 2007-09-13 US disclosed
US-20070213297-A1 Arrays with cleavable linkers SCRIPPS RESEARCH INSTITUTE, THE 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120028249-A1 ANTHRAQUINONE BASED NEAR IR EMITTING COMPOUNDS AND USES THEREOF ANTXR2, AAAS, IK CA12 1502/4885CA1 1493/4885CA9 1207/4885
US-20070213278-A1 Arrays with cleavable linkers ENGASE, ADAM33, SIGLEC7 CA12 68/4885CA1 264/4885CA9 458/4885
US-20100247439-A1 DENDRITIC NANO-ANTIOXIDANTS GPX1, GPX4, LPO CA12 3449/4885CA1 3330/4885CA9 4002/4885
US-20070213297-A1 Arrays with cleavable linkers ENGASE, ADAM33, SIGLEC7 CA12 68/4885CA1 264/4885CA9 458/4885
US-20140066576-A1 SWITCHABLE IONIC ADHESIVE COATING FOR RECYCLABLE CARBON FIBER ILK, VIM, EPCAM CA12 196/4885CA1 101/4885CA9 130/4885
US-20250236607-A1 CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF CDK9, CDK19, CDKL2 CA12 3413/4885CA1 3914/4885CA9 498/4885
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS GALE, SLC2A8, SLC2A4 CA12 253/4885CA1 1185/4885CA9 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.