Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL143653 | 0.93 | KDM4E (0.45) | KDM4EKMT2AMAPTRAB9ANPC1 | |
| SCHEMBL152015 | 0.89 | KMT2A (0.45) | KDM4EKMT2AMAPTRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL145514 | 0.87 | KMT2A (0.43) | KDM4EKMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL144431 | 0.85 | CA12 (0.42) | KDM4EKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL143556 | 0.85 | MAPT (0.44) | KDM4EKMT2AMAPTRAB9ANPC1 | |
| Sulfuric Acid SCHEMBL141954 | 0.84 | KMT2A (0.38) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| Sulfuric Acid SCHEMBL141469 | 0.83 | KMT2A (0.38) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| Sulfuric Acid SCHEMBL143554 | 0.82 | L3MBTL1 (0.38) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| Sulfuric Acid SCHEMBL140272 | 0.80 | KMT2A (0.36) | KMT2AMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL19037386 | 0.79 | KMT2A (0.50) | KMT2AMAPTRAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271302-B1 | BLEACHING AGENT COMPRISING A CATIONIC ACYL PYRIDINIUM DERIVATIVE, A CO-BLEACHING ACTIVATOR, AND HYDROGEN PEROXIDE | HENKEL AG & CO KGAA (DE) | 2017-07-12 | — | — | EP | claimed |
| US-20110232669-A1 | Bleaching with Concomitant Hair Tonicizing | HENKEL AG & CO. KGAA (DE) | 2011-09-29 | — | — | US | claimed |
| US-7981166-B2 | Bleaching agent having cationic acyl pyridinium derivatives, co-bleaching activators and hydrogen peroxide | HENKEL AG & CO. KGAA (DE) | 2011-07-19 | — | — | US | claimed |
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2011-03-03 | — | — | US | claimed |
| US-9693937-B2 | Foil applicator | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20150174019-A1 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | US | disclosed |
| US-8277517-B2 | Lightening agent having cationic acylpyridinium derivatives and certain amino acids | HENKEL AG & CO. KGAA (DE) | 2012-10-02 | — | — | US | disclosed |
| US-8277516-B2 | Lightening agent having cationic acylpyridinium derivatives and certain ammonium compounds | HENKEL AG & CO. KGAA (DE) | 2012-10-02 | — | — | US | disclosed |
| US-20120192890-A1 | LIGHTENING AGENT HAVING CATIONIC ACYLPYRIDINIUM DERIVATIVES AND CERTAIN AMMONIUM COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2012-08-02 | — | — | US | disclosed |
| US-20120192891-A1 | LIGHTENING AGENT HAVING CATIONIC ACYLPYRIDINIUM DERIVATIVES AND CERTAIN AMINO ACIDS | HENKEL AG & CO. KGAA (DE) | 2012-08-02 | — | — | US | disclosed |
| US-8137412-B2 | Bleaching with concomitant hair tonicizing | HENKEL AG & CO. KGAA (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120055500-A1 | Foil Applicator | HENKEL AG & CO. KGAA (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20110232669-A1 | Bleaching with Concomitant Hair Tonicizing | HENKEL AG & CO. KGAA (DE) | 2011-09-29 | — | — | US | disclosed |
| US-8025704-B2 | Matting additive for blond hair dyeing | HENKEL AG & CO. KGAA (DE) | 2011-09-27 | — | — | US | disclosed |
| US-7981166-B2 | Bleaching agent having cationic acyl pyridinium derivatives, co-bleaching activators and hydrogen peroxide | HENKEL AG & CO. KGAA (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | MANNECK HARTMUT | 2011-06-02 | — | — | US | disclosed |
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110047712-A1 | BLEACHING AGENT HAVING CATIONIC ACYL PYRIDINIUM DERATIVES, CO-BLEACHING ACTIVATORS AND HYDROGEN PEROXIDE | F12, KRT18, H1-3 | KDM4E 2827/4885KMT2A 1559/4885MAPT 3525/4885 |
| US-20110126361-A1 | Matting Additive for Blond Hair Dyeing | LDHB, HMBS, HBB | KDM4E 1253/4885KMT2A 920/4885MAPT 2863/4885 |
| US-20120192890-A1 | LIGHTENING AGENT HAVING CATIONIC ACYLPYRIDINIUM DERIVATIVES AND CERTAIN AMMONIUM COMPOUNDS | KRT18, AAAS, KATNAL2 | KDM4E 959/4885KMT2A 735/4885MAPT 485/4885 |
| US-20110232669-A1 | Bleaching with Concomitant Hair Tonicizing | KRT18, KAT7, KAT2B | KDM4E 1089/4885KMT2A 480/4885MAPT 1361/4885 |
| US-20120192891-A1 | LIGHTENING AGENT HAVING CATIONIC ACYLPYRIDINIUM DERIVATIVES AND CERTAIN AMINO ACIDS | ALAD, AADAT, ALDH7A1 | KDM4E 1317/4885KMT2A 991/4885MAPT 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.