Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | GLA | P06280 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713936 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL10705372 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL2061521 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL31355216 | 0.73 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL13753818 | 0.73 | LMNA (0.51) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL28527862 | 0.73 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL15296648 | 0.72 | HPGD (0.52) | KDM4EHPGDSMN1; SMN2MAP2K1MAPT | |
| SCHEMBL140598 | 0.70 | KDM4E (0.61) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL8742188 | 0.70 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL17238832 | 0.70 | POLB (0.53) | ALDH1A1GAAKDM4EGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926728-B1 | OXADIAZINE-SUBSTITUTED ARYLAMIDES | BAYER IP GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| US-8486934-B2 | Oxadiazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120058891-A1 | Oxadizine-Substituted Arylamides | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
| US-8062995-B2 | Dioxazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20090143228-A1 | Dioxazine-and Oxadiazine-Substitude Arylamide | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| EP-1926728-A1 | DIOXAZINE- AND OXADIAZINE-SUBSTITUTED ARYLAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007031213-A1 | DIOXAZINE- AND OXADIAZINE-SUBSTITUTED ARYLAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143228-A1 | Dioxazine-and Oxadiazine-Substitude Arylamide | PRXL2A, AOX1, DDT | ALDH1A1 105/4885GAA 1545/4885KDM4E 2519/4885 |
| US-20120058891-A1 | Oxadizine-Substituted Arylamides | DDT, OXER1, PRXL2A | ALDH1A1 119/4885GAA 1491/4885KDM4E 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.