Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.84 |
| ▸ | EPHA2 | P29317 | 6/20 | 0.84 |
| ▸ | CASP7 | P55210 | 3/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.84 |
| ▸ | VDR | P11473 | 3/20 | 0.84 |
| ▸ | TP53 | P04637 | 2/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.84 |
| ▸ | BLM | P54132 | 2/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | USP2 | O75604 | 2/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | MDM4 | O15151 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.84 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.84 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.84 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.84 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16786249 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL4740099 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL14189960 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL13427830 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL10136303 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL23844885 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| SCHEMBL12251430 | 1.00 | GPBAR1 (0.84) | GPBAR1EPHA2CASP7HIF1AVDR | |
| Lithocholic Acid SCHEMBL24001494 | 0.91 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HIF1AVDR | |
| Lithocholic Acid SCHEMBL22479406 | 0.91 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HIF1AVDR | |
| Lithocholic Acid SCHEMBL23923735 | 0.91 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HIF1AVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233581-A1 | FARNESOID X RECEPTOR MODULATORS | INTERCEPT PHARMACEUTICALS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230174988-A1 | METHODS FOR INDUCING BILE ACID SULFOTRANSFERASE SULT2A FOR TREATING METABOLIC DISORDERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230130602-A1 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | THE BOARDS OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2023-04-27 | — | — | US | disclosed |
| US-9783592-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-20170216316-A1 | FARNESOID X RECEPTOR MODULATORS | INTERCEPT PHARMACEUTICALS INC (US) | 2017-08-03 | — | — | US | disclosed |
| US-20170101434-A1 | FARNESOID X RECEPTOR MODULATORS | INTERCEPT PHARMACEUTICALS, INC. | 2017-04-13 | — | — | US | disclosed |
| US-9611289-B2 | Farnesoid X receptor modulators | INTERCEPT PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | UNIV INDIANA RES & TECH CORP (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127088-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140371190-A1 | Farnesoid X receptor modulators | INTERCEPT PHARMACEUTICALS, INC. | 2014-12-18 | — | — | US | disclosed |
| US-20130143815-A1 | GROWTH HORMONE CONJUGATES | NOVO NORDISK HEALTH CARE AG (CH) | 2013-06-06 | — | — | US | disclosed |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-7276323-B2 | Photoresists, polymers and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-7261993-B2 | Photoresists and processes for microlithography | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | GIPR, GLP1R, GCGR | GPBAR1 12/4885EPHA2 1430/4885CASP7 3681/4885 |
| US-20170101434-A1 | FARNESOID X RECEPTOR MODULATORS | NR1H4, SLC10A1, FXR1 | GPBAR1 4/4885EPHA2 751/4885CASP7 4775/4885 |
| US-20230233581-A1 | FARNESOID X RECEPTOR MODULATORS | NR1H4, GPBAR1, FXR1 | GPBAR1 2/4885EPHA2 570/4885CASP7 4643/4885 |
| US-20230130602-A1 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | CDC37, SI, DAD1 | GPBAR1 469/4885EPHA2 4250/4885CASP7 106/4885 |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | GIPR, GLP1R, GCGR | GPBAR1 12/4885EPHA2 1430/4885CASP7 3681/4885 |
| US-20140371190-A1 | Farnesoid X receptor modulators | NR1H4, GPBAR1, FXR1 | GPBAR1 2/4885EPHA2 570/4885CASP7 4643/4885 |
| US-20130143815-A1 | GROWTH HORMONE CONJUGATES | GHRHR, GHSR, GHITM | GPBAR1 84/4885EPHA2 1310/4885CASP7 3640/4885 |
| US-20170216316-A1 | FARNESOID X RECEPTOR MODULATORS | NR1H4, GPBAR1, FXR1 | GPBAR1 2/4885EPHA2 570/4885CASP7 4643/4885 |
| US-20230174988-A1 | METHODS FOR INDUCING BILE ACID SULFOTRANSFERASE SULT2A FOR TREATING METABOLIC DISORDERS | CYP7A1, CYP27A1, CYP7B1 | GPBAR1 63/4885EPHA2 1609/4885CASP7 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.