Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14390693 | 0.85 | ACMSD (0.46) | HPGDACMSD | |
| SCHEMBL14391017 | 0.79 | ALDH1A1 (0.46) | HPGDKDM4ESMN1; SMN2RXFP1KMT2A | |
| SCHEMBL14390901 | 0.78 | PTGES (0.38) | KDM4ESMN1; SMN2RXFP1KMT2AMEN1 | |
| SCHEMBL3584550 | 0.78 | KMT2A (0.44) | HPGDKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3590359 | 0.78 | KMT2A (0.44) | HPGDKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14392510 | 0.77 | ALDH1A1 (0.39) | HPGDKDM4ESMN1; SMN2RXFP1CYP1A2 | |
| SCHEMBL14391095 | 0.76 | GAA (0.39) | HPGDKDM4ECYP1A2CYP2C19KMT2A | |
| Tromethamine SCHEMBL3598984 | 0.76 | KMT2A (0.42) | HPGDKDM4ESMN1; SMN2KMT2AMEN1 | |
| Tromethamine SCHEMBL3583622 | 0.76 | KMT2A (0.42) | HPGDKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14390696 | 0.76 | MEN1 (0.36) | HPGDKDM4ESMN1; SMN2RXFP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |