Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190996 | 0.81 | MAOA (0.37) | ALOX15ALOX12MAPTLMNAHTT | |
| SCHEMBL30392289 | 0.81 | MAOA (0.37) | ALOX15ALOX12MAPTLMNAHTT | |
| SCHEMBL31204901 | 0.78 | LMNA (0.35) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL10033616 | 0.78 | FFAR4 (0.37) | MAPTLMNASMN1; SMN2MEN1GAA | |
| SCHEMBL13114497 | 0.76 | SMN1; SMN2 (0.53) | ALOX15MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21500712 | 0.76 | ALOX5 (0.31) | NPC1RAB9AALOX5 | |
| SCHEMBL15628793 | 0.75 | ALDH1A1 (0.32) | HPGD | |
| SCHEMBL21500751 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2NPC1RAB9AALOX5 | |
| SCHEMBL18809447 | 0.74 | HSP90AA1 (0.32) | MAPTSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL14541022 | 0.71 | PGR (0.46) | MAPTSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572203-B1 | SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-11-07 | — | — | EP | disclosed |