Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399160 | 0.81 | PPARG (0.43) | ALDH1A1CYP2C19CYP2C9ACACB | |
| SCHEMBL24862943 | 0.80 | NPC1 (0.50) | CYP2C19LMNAL3MBTL1OPRM1OPRD1 | |
| SCHEMBL24862961 | 0.79 | GFER (0.58) | ALDH1A1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL5325964 | 0.79 | POLB (0.61) | ALDH1A1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL24862953 | 0.79 | ALDH1A1 (0.51) | ALDH1A1CYP2C19LMNAOPRM1OPRD1 | |
| SCHEMBL5325161 | 0.76 | ACACB (0.48) | ALDH1A1ACACBL3MBTL1KMT2A | |
| SCHEMBL24862899 | 0.76 | RAB9A (0.67) | ALDH1A1ACACBLMNAOPRM1OPRD1 | |
| SCHEMBL7161710 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP2C19LMNAOPRM1OPRD1 | |
| SCHEMBL14399343 | 0.71 | NPC1 (0.42) | ACACBLMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL14397665 | 0.71 | KMT2A (0.60) | ALDH1A1ACACBLMNAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |