Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11050009 | 0.98 | TYK2 (0.42) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL11884423 | 0.86 | BACE1 (0.46) | TYK2KMT2AGAAPDK1PDK2 | |
| SCHEMBL11879361 | 0.86 | GAA (0.37) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL11883002 | 0.86 | GAA (0.37) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL11497911 | 0.86 | PDK1 (0.46) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL4206477 | 0.84 | TYK2 (0.39) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL11884358 | 0.83 | L3MBTL1 (0.47) | TYK2LMNAPDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL16701798 | 0.82 | TYK2 (0.38) | TYK2LMNAMEN1KMT2AGAA | |
| SCHEMBL11057728 | 0.81 | CYP1A2 (0.49) | TYK2LMNAMEN1KMT2APDK1 | |
| SCHEMBL11074940 | 0.81 | GAA (0.50) | LMNAMEN1KMT2AGAATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008150-B1 | 2,6-DICHLOROPHENYL-SUBSTITUTED AMINO-IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARING SUCH DERIVATIVES AND PHARMACEUTICAL PREPARATIONS COMPRISING SAID DERIVATIVES | Farmos-Yhtyma Oy (FI) | 1982-04-28 | — | — | EP | claimed |
| EP-0008150-A2 | 2,6-Dichlorophenyl-substituted amino-imidazole derivatives, processes of preparing such derivatives and pharmaceutical preparations comprising said derivatives | Farmos-Yhtyma Oy (FI) | 1980-02-20 | — | — | EP | claimed |
| US-12006294-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-06-11 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
| US-9765020-B2 | Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis | CELLIX BIO PRIVATE LIMITED (IN) | 2017-09-19 | — | — | US | disclosed |
| US-9765020-B2 | Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis | CELLIX BIO PRIVATE LIMITED (IN) | 2017-09-19 | — | — | US | disclosed |
| US-9765020-B2 | Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis | CELLIX BIO PRIVATE LIMITED (IN) | 2017-09-19 | — | — | US | disclosed |
| US-20150307446-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | CELLIX BIO PRIVATE LIMITED (IN) | 2015-10-29 | — | — | US | disclosed |
| US-20150307446-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | CELLIX BIO PRIVATE LIMITED (IN) | 2015-10-29 | — | — | US | disclosed |
| US-20150307446-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | CELLIX BIO PRIVATE LIMITED (IN) | 2015-10-29 | — | — | US | disclosed |
| WO-2011029046-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-0405525-A2 | Novel cyanoguanidine derivatives | KANEBO, LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4488993-A | Amidinoureas | WILLIAM H. RORER, INC. | 1984-12-18 | — | — | US | disclosed |
| EP-0008150-B1 | 2,6-DICHLOROPHENYL-SUBSTITUTED AMINO-IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARING SUCH DERIVATIVES AND PHARMACEUTICAL PREPARATIONS COMPRISING SAID DERIVATIVES | Farmos-Yhtyma Oy (FI) | 1982-04-28 | — | — | EP | disclosed |
| US-4275072-A | 2,6-Dichlorophenyl-substituted amino-imidazole derivatives and use as hypertensive agents | FARMOS GROUP, LTD. (FI) | 1981-06-23 | — | — | US | disclosed |
| US-4220658-A | Treatment of hypertension with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0008150-A2 | 2,6-Dichlorophenyl-substituted amino-imidazole derivatives, processes of preparing such derivatives and pharmaceutical preparations comprising said derivatives | Farmos-Yhtyma Oy (FI) | 1980-02-20 | — | — | EP | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | OPRL1, INA, OGFR | TYK2 3643/4885LMNA 1901/4885MEN1 4058/4885 |
| US-12006294-B2 | Therapeutic compounds | OPRL1, INA, OGFR | TYK2 3643/4885LMNA 1901/4885MEN1 4058/4885 |
| US-20150307446-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | MUC1, SI, ALPI | TYK2 3511/4885LMNA 3373/4885MEN1 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.