SCHEMBL297404

SCHEMBL297404

CCOC(=O)C1(N)CC(OCc2ccccc2)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADAM17 P78536 1/20 0.45
EPHX2 P34913 1/20 0.43
NR1H4 Q96RI1 1/20 0.42
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
ALDH1A1 P00352 3/20 0.41
PPID Q08752 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
OPRM1 P35372 5/20 0.40
OPRL1 P41146 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DPP4 P27487 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
OPRD1 P41143 2/20 0.39
OPRK1 P41145 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15306513 1.00 ADAM17 (0.45) ADAM17EPHX2NR1H4TSHRLMNA
SCHEMBL23285147 0.90 ALDH1A1 (0.45) ADAM17EPHX2TSHRLMNAALDH1A1
SCHEMBL23274871 0.86 EPHX2 (0.44) ADAM17EPHX2LMNAALDH1A1CYP3A4
SCHEMBL871442 0.86 ADAM17 (0.46) ADAM17EPHX2NR1H4TSHRLMNA
SCHEMBL15927866 0.85 ADAM17 (0.46) ADAM17EPHX2NR1H4TSHRLMNA
SCHEMBL8050802 0.84 ADAM17 (0.43) ADAM17EPHX2NR1H4TSHRLMNA
SCHEMBL8053435 0.84 ADAM17 (0.45) ADAM17EPHX2NR1H4TSHRLMNA
SCHEMBL12277199 0.84 LMNA (0.46) ADAM17EPHX2TSHRLMNAALDH1A1
SCHEMBL14409083 0.83 GRM2 (0.47) EPHX2ALDH1A1TDP1OPRM1OPRL1
SCHEMBL296907 0.83 GRM2 (0.47) EPHX2ALDH1A1TDP1OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3354639-B1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2024-02-21 EP disclosed
EP-3530648-B1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2023-11-08 EP disclosed
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2021-12-16 US disclosed
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-08-10 US disclosed
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-03-23 US disclosed
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2020-09-10 US disclosed
EP-3530648-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD (JP) 2019-08-28 EP disclosed
EP-2128130-B1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2018-10-10 EP disclosed
US-20180256760-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2018-09-13 US disclosed
EP-3354639-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2018-08-01 EP disclosed
US-7897811-B2 Process for production of radioactive fluorine-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2011-03-01 US disclosed
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-10-14 US disclosed
EP-2230229-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2010-09-22 EP disclosed
WO-2010097374-A1 COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-09-02 WO disclosed
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128130-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2009-12-02 EP disclosed
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-08-06 US disclosed
EP-2017258-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-01-21 EP disclosed
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-11-13 US disclosed
EP-1978015-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180256760-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND FUS, SLC43A1, PFAS ADAM17 4508/4885EPHX2 4033/4885NR1H4 4381/4885
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound FOSB, AFF1, SLCO4C1 ADAM17 3116/4885EPHX2 3141/4885NR1H4 1557/4885
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND AFF1, SLCO4C1, SLCO2A1 ADAM17 4753/4885EPHX2 3456/4885NR1H4 1501/4885
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 ADAM17 4201/4885EPHX2 3113/4885NR1H4 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.