Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.51 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860575 | 0.84 | PHLPP2 (0.55) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| SCHEMBL1098585 | 0.83 | APP (0.69) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| SCHEMBL110351 | 0.83 | APP (0.69) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| SCHEMBL461768 | 0.83 | APP (0.69) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| SCHEMBL7921324 | 0.82 | APP (0.67) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| SCHEMBL10625306 | 0.82 | APP (0.67) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| Orange G SCHEMBL17279088 | 0.81 | APP (0.70) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| Orange G SCHEMBL3020774 | 0.81 | APP (0.70) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| Orange G SCHEMBL3020776 | 0.81 | APP (0.70) | MAPK1ALDH1A1PRMT1ENPP2HIF1A | |
| Orange G SCHEMBL31621938 | 0.81 | APP (0.70) | MAPK1ALDH1A1PRMT1ENPP2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | AMBION, INC (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | RNASE1, RNASEH1, RNASEL | MAPK1 3346/4885ALDH1A1 2603/4885PRMT1 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.