Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914057 | 0.75 | PDGFRB (0.83) | PDGFRBPDGFRA | |
| SCHEMBL19408052 | 0.74 | KMT2A (0.60) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL30964278 | 0.73 | CXCR3 (0.55) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8699733 | 0.69 | KMT2A (0.52) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL5462633 | 0.69 | ALDH1A1 (0.62) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL6132010 | 0.68 | GAA (0.62) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL22289851 | 0.68 | MAPT (0.74) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL6131871 | 0.67 | ALDH1A1 (0.75) | KMT2ALMNAGAAALDH1A1HTT | |
| SCHEMBL6966867 | 0.67 | KMT2A (0.67) | MAPTKMT2AMEN1LMNAGAA | |
| Mefeclorazine SCHEMBL2110367 | 0.66 | ADRA1D (0.73) | KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107352-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2007-09-27 | — | — | WO | disclosed |