Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964289 | 0.84 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL30964256 | 0.81 | HTR1A (0.56) | MAPK1NPC1DRD2DRD3RBP4 | |
| SCHEMBL5462633 | 0.80 | ALDH1A1 (0.62) | NPC1ALDH1A1SMN1; SMN2GFERMEN1 | |
| SCHEMBL30964242 | 0.77 | DRD2 (0.62) | MAPK1DRD2DRD3SMN1; SMN2GFER | |
| SCHEMBL30964248 | 0.76 | DRD2 (0.68) | DRD2DRD3MEN1KMT2AHTR1A | |
| Mefeclorazine SCHEMBL2110367 | 0.73 | ADRA1D (0.73) | MAPK1DRD2DRD3ALDH1A1KMT2A | |
| SCHEMBL14420855 | 0.73 | MAPT (0.69) | MAPK1PDGFRBPDGFRAALDH1A1SMN1; SMN2 | |
| SCHEMBL6131869 | 0.73 | ADRA1D (0.60) | DRD2DRD3RBP4MEN1KMT2A | |
| SCHEMBL30964241 | 0.72 | HTR1A (0.51) | TSHRMAPK1DRD2DRD3RBP4 | |
| SCHEMBL30964267 | 0.72 | TSHR (0.57) | TSHRMAPK1NPC1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |