Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269112 | 0.86 | ACLY (0.59) | P2RX1TLR8RXFP1ACLY | |
| SCHEMBL14428253 | 0.79 | FABP1 (0.56) | — | |
| SCHEMBL28573399 | 0.79 | P2RX1 (0.56) | P2RX1RXFP1MAPTKCNH2 | |
| SCHEMBL2275706 | 0.78 | SERPINE1 (0.58) | MAPK14ACLYKDM4EMAPT | |
| SCHEMBL14428460 | 0.78 | L3MBTL1 (0.60) | TLR8 | |
| SCHEMBL2272613 | 0.77 | LMNA (0.56) | RXFP1MAPK14ACLY | |
| SCHEMBL14428218 | 0.77 | HDAC2 (0.54) | — | |
| SCHEMBL14429564 | 0.77 | SERPINE1 (0.54) | — | |
| SCHEMBL14428494 | 0.77 | PGR (0.66) | MAPT | |
| SCHEMBL13890889 | 0.76 | MTNR1A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |