Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.58 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.57 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.52 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | PYGM | P11217 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272432 | 0.96 | PYGL (0.55) | SERPINE1KCNK2KCNK10MAPK14NPC1 | |
| SCHEMBL2269112 | 0.92 | ACLY (0.59) | SERPINE1KCNK2KCNK10HPSEACLY | |
| SCHEMBL2277696 | 0.91 | MPO (0.59) | KCNK2KCNK10MAPK14HPSEPYGL | |
| SCHEMBL2272613 | 0.90 | LMNA (0.56) | MAPK14NPC1RAB9AKMT2AACLY | |
| SCHEMBL2292297 | 0.89 | KCNK2 (0.62) | SERPINE1KCNK2KCNK10MAPK14NPC1 | |
| SCHEMBL2271588 | 0.88 | SERPINE1 (0.64) | SERPINE1NPC1RAB9AKMT2AHPSE | |
| SCHEMBL2273634 | 0.88 | SERPINE1 (0.60) | SERPINE1KCNK2KCNK10KMT2AHPSE | |
| SCHEMBL2274737 | 0.87 | AVPR2 (0.49) | SERPINE1KCNK2KCNK10MAPK14KMT2A | |
| SCHEMBL2293270 | 0.86 | SERPINE1 (0.70) | SERPINE1KCNK2KCNK10MAPK14NR1H4 | |
| SCHEMBL2276745 | 0.86 | SERPINE1 (0.65) | SERPINE1NPC1RAB9AKMT2AHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | SERPINE1 101/4885KCNK2 3527/4885KCNK10 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.