Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754412 | 0.84 | PDE4D (0.55) | MAPTPDE4D | |
| SCHEMBL13600092 | 0.80 | RAB9A (0.35) | LMNAPOLBCYP1A2MAPTRAB9A | |
| SCHEMBL3277283 | 0.77 | MAPT (0.54) | LMNAALKBH1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13600093 | 0.77 | HTT (0.35) | LMNAPOLBCYP1A2CYP2C9MAPT | |
| SCHEMBL13607159 | 0.73 | LMNA (0.47) | LMNAALKBH1POLBCYP1A2CYP2C9 | |
| SCHEMBL15180443 | 0.71 | ALKBH1 (0.48) | LMNAALKBH1POLBCYP1A2CYP2C9 | |
| SCHEMBL2202029 | 0.69 | POLB (0.59) | POLBMAPTRAB9ANPSR1MEN1 | |
| SCHEMBL2203140 | 0.69 | ALKBH5 (0.49) | LMNAPOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27780413 | 0.69 | ALDH1A1 (0.51) | LMNAALKBH1POLBCYP1A2CYP2C9 | |
| SCHEMBL2938583 | 0.68 | MEN1 (0.69) | POLBCYP1A2CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093515-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN LA-ROCHE AG (CH) | 2007-08-23 | — | — | WO | disclosed |