Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692814 | 0.90 | KCNH2 (0.44) | MAPTCCR5UBE2MDCUN1D1KCNH2 | |
| SCHEMBL4691224 | 0.88 | UBE2M (0.45) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL3281865 | 0.86 | CCR5 (0.52) | ALDH1A1MAPTHTTSMN1; SMN2GAA | |
| SCHEMBL4690404 | 0.86 | CCR5 (0.41) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL4695195 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL4691024 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL4694337 | 0.86 | CCR5 (0.43) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL4691640 | 0.86 | MAPT (0.54) | ALDH1A1MAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL4690668 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL13326676 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191406-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191406-A1 | Heterocyclic antiviral compounds | CCR5, CX3CR1, CXCR1 | ALDH1A1 2289/4885MAPT 4306/4885RAB9A 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.