SCHEMBL144605

SCHEMBL144605

[CH2]C[C](c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.42
MAPK1 P28482 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CES2 O00748 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
MAOA P21397 3/20 0.39
MAOB P27338 3/20 0.39
GSK3B P49841 2/20 0.39
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003390 0.78 MAPT (0.39) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL8110239 0.75 L3MBTL1 (0.46) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL1616425 0.74 MAOA (0.54) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL6003383 0.74 TDP1 (0.41) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL3087344 0.73 CES1 (0.43) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL16429046 0.72 MAPT (0.45) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL338161 0.72 ALDH1A1 (0.41) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL9804382 0.72 CES1 (0.42) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL1174955 0.72 MAOA (0.39) CES1MAPK1CYP3A4MAPTTDP1
SCHEMBL301139 0.72 MAPK1 (0.64) CES1MAPK1CYP3A4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US claimed
US-20190177469-A1 CURABLE RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2019-06-13 US claimed
US-11827796-B2 Curable resin composition for three-dimensional shaping and method of manufacturing three-dimensionally shaped product CANON KABUSHIKI KAISHA (JP) 2023-11-28 US disclosed
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US disclosed
CN-112352017-B Aqueous resin composition and method for producing same DIC株式会社 2023-04-07 CN disclosed
WO-2021024894-A1 AQUEOUS RESIN COMPOSITION AND METHOD FOR PRODUCING SAME DIC株式会社 2021-02-11 WO disclosed
CN-112352017-A Aqueous resin composition and method for producing same DIC株式会社 2021-02-09 CN disclosed
US-20190315981-A1 CURABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND METHOD OF MANUFACTURING THREE-DIMENSIONALLY SHAPED PRODUCT CANON KABUSHIKI KAISHA (JP) 2019-10-17 US disclosed
US-20190177469-A1 CURABLE RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2019-06-13 US disclosed
EP-2428535-A1 THERMOSETTING POLYIMIDE RESIN COMPOSITION, CURED PRODUCT, AND ADHESIVE Mitsubishi Gas Chemical Company, Inc. (JP) 2012-03-14 EP disclosed
US-20120059119-A1 THERMOSETTING POLYIMIDE RESIN COMPOSITION, CURED PRODUCT, AND ADHESIVE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-03-08 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed
EP-1355955-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.p.A. (IT) 2003-10-29 EP disclosed
US-20030027715-A1 Catalyst for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A (IT) 2003-02-06 US disclosed
WO-2002044219-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-06-06 WO disclosed
US-6255532-B1 REACTING PYRILIUM SALTS WITH PHOSPHINE; CONSTANT PRESSURE; ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
US-6252117-B1 NONCATALYTIC REACTION OF PYRILLIUM SALT WITH PHOSPHINE SUPPLIED DURING THE REACTION TO MAINTAIN A UNIFORM PHOSPHINE PARTIAL PRESSURE BASF AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed
EP-0383346-B1 Catalyst, process for its preparation and process for polymerization of olefins using this catalyst SHOWA DENKO KK (JP) 1995-05-03 EP disclosed
US-5041403-A Magnesium, titanium, halogen, ester compound, and organic aluminum compound SHOWA DENKO K.K. (JP) 1991-08-20 US disclosed
EP-0383346-A2 Catalyst, process for its preparation and process for polymerization of olefins using this catalyst SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-08-22 EP disclosed