Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKCH | P24723 | 2/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079295 | 0.75 | CES1 (0.63) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL31241414 | 0.75 | CES1 (0.63) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL6405656 | 0.73 | PARP1 (0.53) | PRKCBPRKCACES1PARP1CDK2 | |
| SCHEMBL14463523 | 0.72 | APAF1 (0.49) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL14463509 | 0.69 | NPSR1 (0.52) | PARP1MEN1KMT2ANPSR1 | |
| SCHEMBL8207983 | 0.68 | PARP1 (0.50) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL14463439 | 0.68 | NPSR1 (0.51) | PARP1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL14463468 | 0.68 | PRKCB (0.53) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL57037 | 0.66 | DNMT1 (0.53) | PRKCBPRKCACES1PARP1CDK2 | |
| SCHEMBL1654813 | 0.66 | ALOX5 (0.51) | PRKCBPRKCAPRKCHPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064345-A9 | HETEROCYCLIC-SUBSTITUTED BIS-1,8 NAPHTHALIMIDE COMPOUNDS, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE | GENENTECH INC (US) | 2007-07-12 | — | — | WO | disclosed |