Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799189 | 0.90 | MMP13 (0.40) | ALDH1A1LMNAJAK2S1PR4HSP90AA1 | |
| SCHEMBL4092235 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNAGAAITGA4ITGB7 | |
| SCHEMBL13799190 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNAGAAITGA4ITGB7 | |
| SCHEMBL6600202 | 0.89 | MMP8 (0.46) | ALDH1A1LMNAHTTGAAITGA4 | |
| SCHEMBL30688558 | 0.82 | ITGB3 (0.45) | ALDH1A1HPGDITGA4ITGB7REN | |
| SCHEMBL22457743 | 0.82 | ITGB3 (0.45) | ALDH1A1HPGDITGA4ITGB7REN | |
| SCHEMBL30688551 | 0.82 | ITGB3 (0.45) | ALDH1A1HPGDITGA4ITGB7REN | |
| SCHEMBL7435174 | 0.81 | MMP13 (0.44) | ALDH1A1LMNAJAK2S1PR4HSP90AA1 | |
| SCHEMBL22457742 | 0.81 | REN (0.40) | ALDH1A1LMNAJAK2S1PR4HSP90AA1 | |
| SCHEMBL14465126 | 0.80 | MMP8 (0.43) | ALDH1A1MMP8EPHX2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077201-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2007-07-12 | — | — | WO | disclosed |